- Case Report
- Two Cases of Wolman's in Siblings
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Joon Sung Kim, Tai Huyng Cho, Hoon Kook, Seung Hee Choi, Young Youn Choi, Chang Soo Park, Heoung Keun Kang, Dong Kyu Jin, Tai Ju Hwang
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Clin Exp Pediatr. 1998;41(4):529-537. Published online April 15, 1998
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Wolman' disease is a rare autosomal recessive disorder in which a deficiency of lysosomal acid lipase leads to the accumulation of cholesteryl esters and trigycerides in most of the body tissues. Clinically, it is characterized by abdominal distention, hepatosplenomegaly, vomiting, intractable diarrgeam steatorrhea, malabsorption, inanitionm failure to thrive, and bilateral enlargement and calcification of the adrenal glands demonstrated by roentgenographic... |
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- Original Article
- Expression of Tumor Suppression Gene in Childhood Cancer
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Ji Eun Lee, Myung Ik Lee, Chang Soo Park
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Clin Exp Pediatr. 1998;41(3):383-389. Published online March 15, 1998
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Purpose : Childhood cancer is closely related to the mutation of tumor suppressor gene. The mutant gene may evoke congenital anomaly and development of cancer. The common solid tumors in childhood are Wilms' tumor, retinoblastoma and neuroblastoma. The cytogenetic study has been performed. The cytogentic study revealed structural abnormality of chromosome in Wilms' tumor and retinoblastoma. The oncogene and mutation... |
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- Case Report
- Two Cases of Chronic Myelocytic Leukemia.
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Hye Keun Kim, Hwa Young Kim, Young Youn Choi, Soon Pal Suh, Chang Soo Park
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Clin Exp Pediatr. 1983;26(2):183-187. Published online February 28, 1983
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The authors experienced two cases of adult type of chronic myelocytic leukemia.
We diagnosed it through the evaluation of both clinical and hematologic features, but
Philadephia chromosomes were not detected. Patients had been treated with my 1 eran followed
by some degree of remission. A brief review of literatures was made.
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